A novel ingredient diet is one that contains ingredients your pet has never eaten before. They aren’t inherently less allergenic – they’re just novel to that pet and therefore won’t trigger an allergy – so it’s important to be aware that what is novel for one dog may not be novel for another. When considering what ingredients your pet has eaten before, it’s important to consider not only the main protein source (meats, etc), but also carbohydrates and other diet ingredients since even ingredients like rice, corn, peas, potatoes, or brewer’s yeast contain protein, which is the component that triggers food allergies. Since oils, vitamins, and minerals don’t contain protein (and are critical for a nutritionally balanced diet), previous exposure to these ingredients typically isn’t considered for novel ingredient diets. Even though there are many “novel ingredient” or “limited ingredient” diets available over-the-counter, I recommend only using a veterinary novel ingredient diet for an elimination diet trial because
several studies have shown high rates of contamination with common proteins in over-the-counter “allergy” or “limited ingredient” diets and many over-the-counter “limited ingredient” diets contain more ingredients than their name implies.